Intimal Thickening and Hyperlipidemia in Experimental Primate Vascular Autografts
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چکیده
منابع مشابه
Intimal thickening in arterial autografts. Role of the adventitial layer.
In the present work, the repairing response of the iliac arterial wall is studied after carrying out autografts in segments of these vessels. The formation of the intimal hyperplasia, which occurred in all the cases, was followed at the biochemical level (tritium thymidine incorporation) and with light and electron microscopy. The adventitial layer showed great activity during the repairing pro...
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I read with great interest the report of Tavora et al. [1], who accurately studied sudden coronary death caused by pathologic intimal thickening without atheromatous plaque formation. In a large institution, over 300 hearts from patients experiencing a sudden unexpected death were studied retrospectively; the authors found that nonatheromatous atherosclerosis accounts for over 10% of sudden cor...
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We studied the influence of hypophyseetomy on endothelial cell regrowth and intimal thickening following aortic endothelial removal. Modification of this influence by replacement doses of glucocorticoids, mineralocorticoids, thyroxin, and growth hormone also was investigated. Young adult male rats were used, and endothelial removal was achieved by the balloon catheter method. Percent endothelia...
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Upregulation of vascular endothelial growth factor (VEGF) expression can inhibit intimal thickening after vascular injury. However, the lack of efficient gene delivery systems leads to insufficient VEGF expression, which prevents its application in gene therapy. In the present study, to improve the delivery of the plasmid vector with the VEGF gene (pVEGF165) to the injured vessel wall, we explo...
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ژورنال
عنوان ژورنال: Annals of Surgery
سال: 1979
ISSN: 0003-4932
DOI: 10.1097/00000658-197901000-00013